QUEBEC: In a significant advancement for dental care, Quebec-based Oral Science has received Health Canada approval (NPN 80129669) for Papacárie Duo, a papain-based enzyme gel designed for minimally invasive and anesthesia-free caries removal. This innovative chemomechanical method offers a patient-friendly alternative to traditional drilling techniques.
How Papacárie Duo Works
Papacárie Duo utilizes papain, a natural enzyme extracted from papaya, to selectively break down denatured collagen in decayed dentin. This process softens carious tissue without affecting healthy tooth structure, allowing for gentle removal using hand instruments. The result is a significant reduction in the need for anesthesia and minimized patient discomfort, making it particularly beneficial for pediatric, geriatric, and special-needs patients.
Clinical Validation
A randomized controlled trial published in the BDJ Open evaluated the efficacy of Papacárie Duo compared to other chemomechanical caries removal agents and traditional rotary methods. The study found that Papacárie Duo effectively removes caries while offering enhanced patient comfort, though it requires a longer treatment time than conventional methods.
Another study in the Indian Journal of Dental Research reported that Papacárie Duo achieved results comparable to traditional low-speed bur methods in primary teeth, with advantages including ease of use and reduced damage to dental tissue.
Implications for Dental Practice
The approval of Papacárie Duo by Health Canada marks a pivotal moment in the adoption of minimally invasive dentistry. By providing a painless and effective alternative to traditional drilling, Papacárie Duo aligns with the principles of atraumatic restorative treatment (ART) and has the potential to improve patient compliance and overall oral health outcomes.